Betulinic Acid-d3

CAS: 472-15-1

Ref. TR-B330252

Product Information

• Name: Betulinic Acid-d3
• Synonyms: Mairin-d3, 3β-Hydroxylup-20(29)-en-28-oic Acid-d3, Betulic Acid-d3, Lupatic Acid-d3, NSC 113090-d3, β-Betulinic Acid-d3, (3β)-3-HydroxyLup-20(29)-en-28-oic Acid-d3
• Brand: TRC
• Description: Applications Betulinic Acid-d3 is the isotope labelled analog of Betulinic Acid (B330250); a natural pentacyclic triterpenoid that displays anti-inflammatory and anti-HIV activity. Betulinic Acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activity.References Pisha, E. et al.: Nat. Med., 1, 1046 (1995); Fulda, S. et al.: Cancer Res., 57, 4956 (1997); Kashiwada, Y. et al.: J. Med. Chem., 39, 1016 (1996); Genet, C. et al.: J. Med. Chem., 53, 178 (2010)

Chemical properties

• Molecular weight: 459.72
• Formula: C₃₀H₄₅D₃O₃
• Color/Form: Neat
• InChI: InChI=1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23+,24+,27-,28+,29+,30-/m0/s1/i12D2,23D
• InChI key: InChIKey=QGJZLNKBHJESQX-REXYKOGVSA-N
• SMILES: [2H]C1([2H])C[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2CC[C@@H]2[C@H]4[C@H](C(=C)C)CC[C@]4(C(=O)O)CC[C@]23C)C(C)(C)[C@@]1([2H])O