Bevirimat

CAS: 174022-42-5

Ref. TR-B334700

Product Information

• Name: Bevirimat
• Synonyms: 3-O-(3',3'-Dimethylsuccinyl)betulinic acid, FH 11327, O-(3,3-Dimethylsuccinyl)betulinic Acid, PA 457, YK FH312, (3β)-3-(3-Carboxy-3-methyl-1-oxobutoxy)lup-20(29)-en-28-oic acid, 3-O-(3′,3′-Dimethylsuccinyl)betulinic acid, 3beta-(3-Carboxy-3-methylbutanoyloxy)lup-20(29)-en-28-oic acid 3β-(3-Carboxy-3-methylbutyryloxy)lup-20(29)-en-28-oic acid O-(3,3-Dimethylsuccinyl)betulinic acid, Bevirimat Dimeglumine, Fh 11327, Lup-20(29)-en-28-oic acid, 3-(3-carboxy-3-methyl-1-oxobutoxy)-, (3β)-, Mp 4326, O-(3,3-Dimethylsuccinyl)betulinic acid, Pa-457, Yk-Fh312
• CAS: 174022-42-5

Description

Applications Bevirimat is a HIV-1 maturation inhibitor, targetting the Gag CA-SP1 cleavage site. HIV Inhibitor.
References Coric, P. et al.: Eur. J. Med. Chem., 62, 453 (2013); Waki, K. et al.: PLoS Path., 8, e1002997 (2012);

• Brand: TRC

Chemical properties

• Molecular weight: 584.83
• Formula: C₃₆H₅₆O₆
• Color/Form: Neat
• InChI: InChI=1S/C36H56O6/c1-21(2)22-12-17-36(30(40)41)19-18-34(8)23(28(22)36)10-11-25-33(7)15-14-26(42-27(37)20-31(3,4)29(38)39)32(5,6)24(33)13-16-35(25,34)9/h22-26,28H,1,10-20H2,2-9H3,(H,38,39)(H,40,41)/t22?,23-,24+,25-,26+,28-,33+,34-,35-,36+/m1/s1
• InChI key: InChIKey=MLZIFGYKDWQAAK-SSFKTDSYSA-N
• SMILES: C=C(C)[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(=O)CC(C)(C)C(=O)O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12