Product Information
Name:N-Biotinylaminoethyl Methanethiosulfonate
Controlled Product
Synonyms:
- 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-(2-methylsulfonylsulfanylethyl)pentanamide
Brand:TRC
Description:Stability Moisture SensitiveApplications Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease. MTSEA-biotin has recently been used to probe the topology of the serotonin (5-HT) transporter by site-directed chemical labelling.References J. Biol. Chem., 273(20), 12675 (1998), Adams, C.M., et al.: J. Biol. Chem., 273 (46), 30204 (1998), Boileau, A. J., et al.: J. Neurosci., 19, 12, 4847 (1999), Wagner, D.A.and Czajkowski, C.: J. Neurosci., 21, 67 (2001), Traebert, M.: J. Membr. Biol., 180, 83 (2001)
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Chemical properties
Molecular weight:381.53
Formula:C13H23N3O4S3
Color/Form:Neat
InChI:InChI=1S/C13H23N3O4S3/c1-23(19,20)22-7-6-14-11(17)5-3-2-4-10-12-9(8-21-10)15-13(18)16-12/h9-10,12H,2-8H2,1H3,(H,14,17)(H2,15,16,18)/t9-,10-,12-/m0/s1
InChI key:InChIKey=CQPWMXNDGWWWHG-NHCYSSNCSA-N
SMILES:CS(=O)(=O)SCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
Technical inquiry about: N-Biotinylaminoethyl Methanethiosulfonate
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