O-Benzyl Ganciclovir N-Formyl Diacetate Dimer

Ref. TR-B412340

Product Information

• Name: O-Benzyl Ganciclovir N-Formyl Diacetate Dimer
• Synonyms: [3-acetyloxy-2-[[2-[[[9-(1,3-diacetyloxypropan-2-yloxymethyl)-6-phenylmethoxypurin-2-yl]-formylamino]methyl-formylamino]-6-phenylmethoxypurin-9-yl]methoxy]propyl] acetate
• Brand: TRC
• Description: Applications O-Benzyl Ganciclovir N-Formyl Diacetate Dimer is an intermediate used in the synthesis of Valganciclovir N3,N3'-Methylene Dimer (>90%) (V092015), which is an impurity of Valganciclovir (V092000), a pro-drug of Ganciclovir (G235000) . Used in treatment of retro-virus.References Acosta, E., et al.: Clin. Pharmacol. Ther., 81, 867 (2007), Nassetta, L., et al.: J. Antimicrob. Chemother., 63, 862 (2009),

Chemical properties

• Molecular weight: 926.884
• Formula: C₄₃H₄₆N₁₀O₁₄
• Color/Form: Neat
• InChI: InChI=1S/C43H46N10O14/c1-28(56)60-17-34(18-61-29(2)57)66-26-50-21-44-36-38(50)46-42(48-40(36)64-15-32-11-7-5-8-12-32)52(24-54)23-53(25-55)43-47-39-37(41(49-43)65-16-33-13-9-6-10-14-33)45-22-51(39)27-67-35(19-62-30(3)58)20-63-31(4)59/h5-14,21-22,24-25,34-35H,15-20,23,26-27H2,1-4H3
• InChI key: InChIKey=JUDOGDJLQCQCES-UHFFFAOYSA-N
• SMILES: CC(=O)OCC(COC(C)=O)OCn1cnc2c(OCc3ccccc3)nc(N(C=O)CN(C=O)c3nc(OCc4ccccc4)c4ncn(COC(COC(C)=O)COC(C)=O)c4n3)nc21