Product Information
Name:1,3-Bis(carboxymethyl)-1H-imidazolium
Controlled Product
Synonyms:
- 2-(1-(Carboxymethyl)-1H-imidazol-3-ium-3-yl)acetate
Brand:TRC
Description:Applications 1,3-Bis(carboxymethyl)-1H-imidazolium is an intermediate in synthesizing 1,3-Bis(2-hydroxy-2,2-diphosphonoethyl)-imidazolium Soidum Salt(Zoledronic Acid Impurity) (B443840), which is an impurity of Zolendronic Acid (trihydrate: Z623501), a biphosphonate that is used for the management of osteoporosis and the treatment of bone metastases from various types of cancers.References Kohno, N., et al.: J. Clin. Oncol., 23, 3314 (2005); Reid, I., et al.: New Engl. J. Med., 346, 653 (2002); Rosen. L., et al.: Cancer J., 7, 377 (2000)
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Chemical properties
Molecular weight:184.15
Formula:C7H8N2O4
Color/Form:Neat
InChI:InChI=1S/C7H8N2O4/c10-6(11)3-8-1-2-9(5-8)4-7(12)13/h1-2,5H,3-4H2,(H-,10,11,12,13)
SMILES:O=C([O-])C[n+]1ccn(CC(=O)O)c1
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