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1,3-Bis(2-chloroethyl)urea
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1,3-Bis(2-chloroethyl)urea

CAS: 2214-72-4

Ref. TR-B419015

1g
1,261.00 €
25mg
319.00 €
Estimated delivery in United States, on Thursday 8 Aug 2024

Product Information

Name:
1,3-Bis(2-chloroethyl)urea
Synonyms:
  • Urea
  • N,N'-bis(2-chloroethyl)-
  • Urea
  • 1,3-bis(2-chloroethyl)- (6CI,7CI,8CI)
  • NSC 36198
  • Urea, N,N'-bis(2-chloroethyl)-
  • Ai3-08682
  • Nsc 36198
  • Urea, 1,3-bis(2-chloroethyl)-
Description:

Stability Hygroscopic, Unstable in Solution
Applications 1,3-Bis(2-chloroethyl)urea is an impurity in the synthesis of Carmustine (C183875), an alkylating and carbamoylating nitrosourea compound. It interacts with DNA, RNA and proteins causing DNA interstrand cross linking which is cytotoxic and leads to apoptotic cell death.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Stahl, et al.: Chem. Res. Toxicol., 5, 106 (1992), Kokkinakis, D.M., et al.: Clin. Cancer Res., 5(11), 3676 (1999), Hickman, M.J., et al.: Proc. Natl. Acad. Sci. USA, 96(19), 10764 (1999),

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
185.05
Formula:
C5H10Cl2N2O
Color/Form:
Neat
InChI:
InChI=1S/C5H10Cl2N2O/c6-1-3-8-5(10)9-4-2-7/h1-4H2,(H2,8,9,10)
InChI key:
InChIKey=VBWBRZHAGLZNST-UHFFFAOYSA-N
SMILES:
O=C(NCCCl)NCCCl
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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