1,4-Bis[(4-chlorophenyl)phenylmethyl]piperazine Dihydrochloride

CAS: 856841-95-7

Ref. TR-B419060

Product Information

• Name: 1,4-Bis[(4-chlorophenyl)phenylmethyl]piperazine Dihydrochloride
• Synonyms: USP Cetirizine Dimer Dihydrochloride, Cetririzine EP Impurity D Dihydrochloride
• Brand: TRC

Description

Impurity Cetririzine EP Impurity D Dihydrochloride
Applications 1,4-Bis[(4-chlorophenyl)phenylmethyl]piperazine Dihydrochloride is an impurity of Buclizine (B689450), an antiemetic agent.
References Birendra, Y., et al.: J. Pharma. Res., 3, 2817 (2010);

Chemical properties

• Molecular weight: 560.38
• Formula: C₃₀H₃₀Cl₄N₂
• Color/Form: Neat
• InChI: InChI=1S/C30H28Cl2N2.2ClH/c31-27-15-11-25(12-16-27)29(23-7-3-1-4-8-23)33-19-21-34(22-20-33)30(24-9-5-2-6-10-24)26-13-17-28(32)18-14-26;;/h1-18,29-30H,19-22H2;2*1H
• InChI key: InChIKey=DLEQNCKNBPYHEY-UHFFFAOYSA-N
• SMILES: Cl.Cl.Clc1ccc(C(c2ccccc2)N2CCN(C(c3ccccc3)c3ccc(Cl)cc3)CC2)cc1