TR-B433855 - bis2-ethylhexyl-4-bromoisophthalate

<p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>

<p>Dimethyl 5-bromoisophthalate is used as pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU ref</p>

Dimethyl 4-Bromoisophthalate

Diethyl 5-Bromoisophthalate

Di-tert-Butyl 5-bromoisophthalate

5-Bromoisophthalic acid

Dimethyl 5-bromoisophthalate

2-Bromoisophthalic acid

4-Bromoisophthalic acid

Dimethyl 2-bromoisophthalate

4-Bromoisophthalic acid is a molecule with a carboxyl group at one end, and a bromine and an isophthalic acid group at the other. It has been shown to bind to the 5-HT7 receptor, which regulates the release of glutamate in neurons and affects the concentration of Ca2+ within cells. 4-Bromoisophthalate inhibits bacterial enzyme carboxylesterase using a mechanism that involves hydrogen bonding interactions. This inhibition prevents the breakdown of 3-mercaptopropionic acid, which would otherwise inhibit Pparγ activation. The structural similarity between 4-bromoisophthalate and xanthinol nicotinate (XNT) was observed by FTIR spectroscopy, allowing for asymmetric synthesis of this molecule.