1-Bis(4-fluorophenyl)methyl Piperazine-d8

CAS: 27469-60-9

Ref. TR-B434877

Product Information

• Name: 1-Bis(4-fluorophenyl)methyl Piperazine-d8
• Synonyms: 1-[Bis(p-fluorophenyl)methyl]piperazine-d8, 1-(Di-p-fluorobenzhydryl)piperazine-d8, 4-[Bis(4-fluorophenyl)methyl]piperazine-d8, N-(4,4'-Difluorobenzhydryl)piperazine-d8, N-(Bis(4-fluorophenyl)methyl)piperazine-d8, R 19352-d8, T 841-d8, 1-(4,4'-Difluorobenzhydryl)Piperazine, 1-(Di-p-fluorobenzhydryl)piperazine, 1-[Bis(4-Fluorophenyl)Methyl]Piperazinediium, 4,4'-Difluorobenzhydrylpiperazine, 4-[Bis(4-fluorophenyl)methyl]piperazine, Di(4-fluorophenyl)methyl piperazine, N-(4,4-Difluorobenzhydryl)piperazine, N-(Bis(4-fluorophenyl)methyl)piperazine, Piperazine, 1-[bis(4-fluorophenyl)methyl]-, Piperazine, 1-[bis(p-fluorophenyl)methyl]-, R 19352, T 841
• CAS: 27469-60-9

Description

Applications 1-Bis(4-fluorophenyl)methyl Piperzaine-d8 is a labelled analogue of 1-Bis(4-fluorophenyl)methyl Piperzaine (B434875), which is a chemical reagent used in the synthesis of novel tubulin polymerization inhibitors. Also used in the synthesis of novel benzhydrylpiperazine carboxamide derivatives. Impurity of F455200. It is also an intermediate in synthesizing Flunarizine-d8 Dihydrochloride (F455202), which is a calcium channel blocker; fluorinated derivative of Cinnarizine. Vasodilator (cerebral and peripheral).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yin, Y. et al.: Bioorg. Med. Chem., 22, 2409 (2014); Gurdal, E. et al.: J. Enz. Inhib. Med. Chem., 29, 205 (2014); Desmedt, L.K., et al.: Arzneim.-Forsch., 25, 1408 (1975); Godfraind, T., et al.: Eur. J. Pharmacol., 53, 273 (1979); Nihard, P., et al.: Angiology, 33, 37 (1982); Holmes, B., et al.: Drugs, 27, 6 (1984);

• Brand: TRC

Chemical properties

• Molecular weight: 296.38
• Formula: C₁₇H₁₀D₈F₂N₂
• Color/Form: Neat
• InChI: InChI=1S/C17H18F2N2/c18-15-5-1-13(2-6-15)17(21-11-9-20-10-12-21)14-3-7-16(19)8-4-14/h1-8,17,20H,9-12H2/i9D2,10D2,11D2,12D2
• InChI key: InChIKey=TTXIFFYPVGWLSE-PMCMNDOISA-N
• SMILES: [2H]C1([2H])NC([2H])([2H])C([2H])([2H])N(C(c2ccc(F)cc2)c2ccc(F)cc2)C1([2H])[2H]