Bisindolylmaleimide VIII Acetic Acid Salt
CAS: 138516-31-1
Ref. TR-B448500
| 10mg | 310.00 € | ||
| 100mg | 1,998.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Product Information
Name:
Bisindolylmaleimide VIII Acetic Acid Salt
Controlled Product
Synonyms:
- 3-[1-(3-Aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione Acetic Acid Salt
- Ro 31-7549 Acetic Acid Salt
- Ro 31-7549/001 Acetic Acid Salt
- 1H-pyrrole-2,5-dione, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-, acetate (1:1)
Description:
Applications It is a potent inhibitor of protein kinase C (PKC) activity. Bisindolylmaleimide VIII (Bis VIII) has been previously shown to enhance Fas-mediated apoptosis through a protein kinase C-independent mechanism.
References Emery, J., et al.: J. Biol. Chem., 273, 14363 (1998), Wiley, S., et al.: Immunity, 3, 673 (1995), MacFarlane, M., et al.: Biochem. J., 348, 93 (2000),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
458.51
Formula:
C26H26N4O4
Color/Form:
Neat
InChI:
InChI=1S/C24H22N4O2.C2H4O2/c1-27-13-17(15-7-2-4-9-19(15)27)21-22(24(30)26-23(21)29)18-14-28(12-6-11-25)20-10-5-3-8-16(18)20;1-2(3)4/h2-5,7-10,13-14H,6,11-12,25H2,1H3,(H,26,29,30);1H3,(H,3,4)
InChI key:
InChIKey=VEOXVBTXROWDAH-UHFFFAOYSA-N
SMILES:
CC(=O)O.Cn1cc(C2=C(c3cn(CCCN)c4ccccc34)C(=O)NC2=O)c2ccccc21
MDL:
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