(2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]-butanedioic Acid with (1R)-1-(3-Aminopropyl)-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile (Mixture)

CAS: 928652-49-7

Ref. TR-B494835

Product Information

• Name: (2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]-butanedioic Acid with (1R)-1-(3-Aminopropyl)-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile (Mixture)
• Synonyms: (3S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol;hydrochloride
• Brand: TRC
• Description: Applications (2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]-butanedioic Acid with (1R)-1-(3-Aminopropyl)-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile is an intermediate in the synthesis of (R)-Citalopram Oxalate (C505015) which is an inhibitor of serotonin (5-HT) uptake. Antidepressant.References Christensen, A.V., et al.: Eur. J. Pharmacol., 41, 153 (1977), Keller, M.B., et al.: J. Clin. Psychiatry, 61, 896 (2000), Von Moltke, L.L., et al.: Drug Metab. Dispos., 29, 1102 (2001), Fish, E.W., et al.: J. Pharmacol. Exp. Ther, 308, 474 (2004),

Chemical properties

• Molecular weight: 243.685
• Formula: C₈H₁₇NO₅·HCl
• Color/Form: Neat
• InChI: InChI=1S/C8H17NO5.ClH/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11;/h5-8,10-14H,1-4H2;1H/t5?,6?,7-,8?;/m0./s1
• InChI key: InChIKey=QHWGCVIAMMMOPR-FHCFQYKESA-N
• SMILES: Cl.OCCN1CC(O)C(O)[C@@H](O)C1CO