Bisoprolol Hemifumarate

CAS: 104344-23-2

Ref. TR-B510500

Product Information

• Name: Bisoprolol Hemifumarate
• Synonyms: Bisoprolol Fumarate, (2R)-1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol, 1-(4-((2-Isopropoxyethoxy)methyl)phenoxy)-3-(isopropylamino)propan-2-ol hemifumarate, 1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol (2E)-but-2-enedioate (2:1) (salt), 1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol (2E)-but-2-enedioate (salt), 1-(Propan-2-Ylamino)-3-(4-{[2-(Propan-2-Yloxy)Ethoxy]Methyl}Phenoxy)Propan-2-Ol, 2-Propanol, 1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-, (2E)-2-butenedioate (2:1), 2-Propanol, 1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-, (2E)-2-butenedioate (2:1) (salt), 2-Propanol, 1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-, (E)-2-butenedioate (2:1) (salt), Bisoprolol fumerate, Concor, Detensiel, Emcor, Emd 33512, Emvoncor, Eurtadal, Isoten, Maintate, Monocor, Soprol, Zebeta

Description

Applications A selective β-adrenergic blocker. Used as an antihypertensive.
References Tattersfield, A.E., et al.: Brit. J. Clin. Pharmacol., 18, 343 (1984), Kohli, R.S., et al.: Eur. Heart J., 6, 845 (1985), Zachariah, P.K., et al.: Clin. Ther., 15, 779 (1993),

• Brand: TRC

Chemical properties

• Molecular weight: 766.9582
• Formula: C₁₈H₃₁NO₄·C₄H₄O₄
• Color/Form: White
• InChI: InChI=1S/2C18H31NO4.C4H4O4/c2*1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4;5-3(6)1-2-4(7)8/h2*5-8,14-15,17,19-20H,9-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+
• InChI key: InChIKey=VMDFASMUILANOL-WXXKFALUSA-N
• SMILES: CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1.CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1.O=C(O)/C=C/C(=O)O