N,O-Bis(trimethylsilyl)acetamide

CAS: 10416-59-8

Ref. TR-B588675

Product Information

• Name: N,O-Bis(trimethylsilyl)acetamide
• Synonyms: BSA, BSiA, Bis(trimethylsilyl)acetamide, Bis(trimethylsilyl)acetimidate, Dynasylan, BSA, LS 7270, N,O-Bis(trimethylsillyl)acetamide, N-(Trimethylsilyl)acetimidic Acid Trimethylsilyl Ester, N-(Trimethylsilyl)ethanimidic Acid Trimethylsilyl Ester, O,N-Bis(trimethylsilyl)acetamide
• Brand: TRC

Description

Applications N,O-Bis(trimethylsilyl)acetamide is used as a reagent in the synthesis of 4'-spirocyclic phosphono-nucleosides as potential inhibitors of hepatitis C virus NS5B polymerase. Also used as a reagent in the microwave-assisted synthesis of purine nucleosides as selective cholinesterase inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Dang, Q., et al.: Tetrahedron Lett., 55, 4407 (2014); Schwarz, S., et al.: Org. Biomol. Chem., 12, 2446 (2014)

Chemical properties

• Molecular weight: 203.43
• Formula: C₈H₂₁NOSi₂
• Color/Form: Neat
• InChI: InChI=1S/C8H21NOSi2/c1-8(9-11(2,3)4)10-12(5,6)7/h1-7H3
• InChI key: InChIKey=SIOVKLKJSOKLIF-CMDGGOBGSA-N
• SMILES: C/C(=N\[Si](C)(C)C)O[Si](C)(C)C