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BIX 01294 Trihydrochloride

CAS:

Ref. TR-B591600

250mg
2,087.00€
BIX 01294 Trihydrochloride
TRC

    Product Information

    Name:BIX 01294 Trihydrochloride
    Controlled Product
    Synonyms:
    • 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine Trihydrochloride
    Brand:TRC
    Description:Applications BIX 01294 Trihydrochloride is a G9a-like protein and G9a histone lysine methyltransferase (HMTase) inhibitor that H3K9me2 chromatin levels modulates H3K9me2 levels in mammalian cells and potentiates induction of pluripotent stem cells from somatic cells in vitro.References Kubicek, S. et al.: Mol. Cell., 25, 473 (2007); Huangfu, D et al.: Nat. Biotechnol., 26, 795 (2008); Chang, Y. et al.: Bat. Struct. Mol. Biol., 16, 312 (2009);
    Notice:Our products are intended for lab use only. For any other use, please contact us.

    Chemical properties

    Molecular weight:600.023
    Formula:C28H38N6O2·3ClH
    Color/Form:Neat
    InChI:InChI=1S/C28H38N6O2.3ClH/c1-32-12-7-13-34(17-16-32)28-30-24-19-26(36-3)25(35-2)18-23(24)27(31-28)29-22-10-14-33(15-11-22)20-21-8-5-4-6-9-21;;;/h4-6,8-9,18-19,22H,7,10-17,20H2,1-3H3,(H,29,30,31);3*1H
    InChI key:InChIKey=BZOWJAYUMMHCDW-UHFFFAOYSA-N
    SMILES:COc1cc2nc(N3CCCN(C)CC3)[nH]c(=NC3CCN(Cc4ccccc4)CC3)c2cc1OC.Cl.Cl.Cl.O

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