tert-Butyl ((2S,3R,E)-3-hydroxy-1-((2-oxido-1,3,2-dioxaphospholan-2-yl)oxy)octadec-4-en-2-yl)carbamate

Ref. TR-B651745

Product Information

• Name: tert-Butyl ((2S,3R,E)-3-hydroxy-1-((2-oxido-1,3,2-dioxaphospholan-2-yl)oxy)octadec-4-en-2-yl)carbamate
• Synonyms: tert-butyl N-[(E,2S,3R)-3-hydroxy-1-[(2-oxo-1,3,2?5-dioxaphospholan-2-yl)oxy]octadec-4-en-2-yl]carbamate

Description

Applications tert-Butyl ((2S,3R,E)-3-hydroxy-1-((2-oxido-1,3,2-dioxaphospholan-2-yl)oxy)octadec-4-en-2-yl)carbamat is an intermediate for the synthesis of D-erythro-Sphingosylphosphorylcholine (S681700), which is involved in cell regulation, and transmembrane signaling. A putative lipid second messenger, connected via Protein Kinase C to the phosphatidylinositol-derived second messengers for signal transduction.
References Kratzer, B. and Schmidt, R.R.: Liebigs Ann., 955-963 (1995)

• Brand: TRC

Chemical properties

• Molecular weight: 505.625
• Formula: C₂₅H₄₈NO₇P
• Color/Form: Neat
• InChI: InChI=1S/C25H48NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)22(26-24(28)33-25(2,3)4)21-32-34(29)30-19-20-31-34/h17-18,22-23,27H,5-16,19-21H2,1-4H3,(H,26,28)/b18-17+/t22-,23+/m0/s1
• InChI key: InChIKey=DJPZSSGHEAWWEP-HXSWCURESA-N
• SMILES: CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](COP1(=O)OCCO1)NC(=O)OC(C)(C)C