N-Boc-p-nitro-L-phenylalanine

CAS: 33305-77-0

Ref. TR-B658040

Product Information

• Name: N-Boc-p-nitro-L-phenylalanine
• Synonyms: N-[(1,1-Dimethylethoxy)carbonyl]-4-nitro-L-phenylalanine, L-N-Carboxy-3-(p-nitrophenyl)alanine N-tert-Butyl Ester, (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-nitrophenyl)propanoic Acid, (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-nitrophenyl)propionic Acid, (S)-2-(tert-Butoxycarbonylamino)-3-(4-nitrophenyl)propanoic Acid, (S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-nitrophenyl)propionic Acid, 2-(S)-[(tert-Butoxycarbonyl)amino]-3-(4-nitrophenyl)propionic Acid, N-(tert-Butoxycarbonyl)-4-nitro-L-phenylalanine, N-(tert-Butyloxycarbonyl)-p-nitro-L-phenylalanine, N-tert-Butoxycarbonyl-p-nitro-L-phenylalanine, (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-nitrophenyl)propanoic acid, (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-nitrophenyl)propionic acid, (S)-2-(tert-Butoxycarbonylamino)-3-(4-nitrophenyl)propanoic acid, (S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-nitrophenyl)propionic acid, 2-(S)-[(tert-Butoxycarbonyl)amino]-3-(4-nitrophenyl)propionic acid, <span class="text-smallcaps">L</span>-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-4-nitro-, Alanine, N-carboxy-3-(p-nitrophenyl)-, N-tert-butyl ester, <span class="text-smallcaps">L</span>-, BOC-L-4-Nitrophe, Boc-L-4-Nitrophenylalanine, Boc-Phe(4-NO2)-OH, D-Phe.otBu.HCl, N-(tert-Butoxycarbonyl)-4-nitro-<span class="text-smallcaps">L</span>-phenylalanine, N-(tert-Butyloxycarbonyl)-p-nitro-<span class="text-smallcaps">L</span>-phenylalanine, N-Boc-p-nitro-<span class="text-smallcaps">L</span>-phenylalanine, N-[(1,1-Dimethylethoxy)carbonyl]-4-nitro-<span class="text-smallcaps">L</span>-phenylalanine, N-tert-Butoxycarbonyl-p-nitro-<span class="text-smallcaps">L</span>-phenylalanine, L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-4-nitro-, Alanine, N-carboxy-3-(p-nitrophenyl)-, N-tert-butyl ester, L-

Description

Applications N-Boc-p-nitro-L-phenylalanine is the N-Boc protected form of p-Nitro-L-phenylalanine (N502725, Hydrate) and is a useful synthetic intermediate in the synthesis of Hydroxymelphalan (H939850); an analog of Melphalan (M216900) which is an antineoplastic.
References Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966), Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980)

• Brand: TRC

Chemical properties

• Molecular weight: 310.3
• Formula: C₁₄H₁₈N₂O₆
• Color/Form: Neat
• InChI: InChI=1S/C14H18N2O6/c1-14(2,3)22-13(19)15-11(12(17)18)8-9-4-6-10(7-5-9)16(20)21/h4-7,11H,8H2,1-3H3,(H,15,19)(H,17,18)/t11-/m0/s1