N-Boc-L-proline

CAS: 15761-39-4

Ref. TR-B664200

Product Information

• Name: N-Boc-L-proline
• Synonyms: (2S)-1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester,(S)-1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, L-1,2-Pyrrolidinedicarboxylic acid, 1-tert-butyl ester, (2S)-1,2-Pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester, (2S)-1-Boc-pyrrolidine-2-carboxylic acid, (2S)-1-tert-Butoxycarbonylpyrrolidine-2-carboxylic acid, (S)-1-(tert-Butoxycarbonyl)-2-pyrrolidinecarboxylic acid, (S)-1-(tertbutoxycarbonyl)pyrrolidine-2-carboxylic acid, (S)-1-Boc-beta-proline, (S)-N-tert-Butoxycarbonylproline, (S)-Pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester, 1-(tert-Butoxycarbonyl)-(S)-proline, 1-tert-Butoxycarbonyl-L-proline, 1-tert-Butyl (S)-pyrrolidine-1,2-dicarboxylate, 1-tert-Butyloxycarbonyl-L-proline, BOC-L-Proline, Boc-L-Pro-OH, L-N-Boc-proline, N-(t-Butoxycarbonyl)proline, N-(tert-Butoxycarbonyl)-(S)-proline, N-(tert-Butoxycarbonyl)-L-proline, N-(tert-Butoxycarbonyl)proline, N-(tert-Butyloxycarbonyl)-L-proline, N-Boc-(S)-proline, N-[(1,1-Dimethylethoxy)carbonyl]-(S)-proline, NSC 164660, (2S)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylate, (2S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid, (S)-1,2-Pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester, (S)-1-Boc-β-proline, 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)-, 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (S)-, 1,2-Pyrrolidinedicarboxylic acid, 1-tert-butyl ester, <span class="text-smallcaps">L</span>-, 1,2-Pyrrolidinedicarboxylic acid, 1-tert-butyl ester, L-, 1-(Tert-Butoxycarbonyl)Proline, 1-(tert-Butoxycarbonyl)-(2S)-pyrrolidine-2-carboxylic acid, 1-(tert-Butyl)hydrogen-(S)-pyrrolidin-1,2-dicarboxylat, 1-(tert-butoxycarbonyl)-L-proline, 1-(tert-butyl) hydrogen (S)-pyrrolidine-1,2-dicarboxylate, 1-Boc-L-Proline, 1-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-proline, 1-tert-Butyloxycarbonyl-<span class="text-smallcaps">L</span>-proline, <span class="text-smallcaps">L</span>-N-Boc-proline, BOC-<span class="text-smallcaps">L</span>-Proline, Boc-<span class="text-smallcaps">L</span>-Pro, Boc-Pro-OH, Hydrogeno-(S)-pyrrolidine-1,2-dicarboxylate de 1-(tert-butyle), N-(tert-Butoxycarbonyl)-<span class="text-smallcaps">L</span>-proline, N-(tert-Butyloxycarbonyl)-<span class="text-smallcaps">L</span>-proline, N-Boc-<span class="text-smallcaps">L</span>-proline, N-alpha-tert-BOC-L-proline, Nsc 164660, hidrogeno-(S)-pirrolidina-1,2-dicarboxilato de 1-(terc-butilo), tert-Butoxycarbonyl-L-proline, tert-Butyloxycarbonyl-L-proline, trans-N-(tert-Butoxycarbonyl)-4-hydroxy-<span class="text-smallcaps">L</span>-proline

Description

Applications N-Boc-L-proline is a useful synthetic intermediate. It is used to synthesize Daclatasvir (D101500) which nhibits the HCV protein NS5A. Daclatasvir (D101500) can be used as a drug candidate for the treatment of hepatitis C (HCV).
References Gao, M., et al.: Nature, 465(7294), 96 (2010); Bell, T. W., Chem. Med. Chem., 5(10), 1663 (2010);

• Brand: TRC

Chemical properties

• Molecular weight: 215.25
• Formula: C₁₀H₁₇NO₄
• Color/Form: Neat
• InChI: InChI=1S/C10H17NO4/c1-10(2,3)15-9(14)11-6-4-5-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)/t7-/m0/s1
• InChI key: InChIKey=ZQEBQGAAWMOMAI-ZETCQYMHSA-N
• SMILES: CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)O