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(1R,2R)-Bortezomib
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(1R,2R)-Bortezomib

CAS: 1132709-15-9

Ref. TR-B675705

5mg
276.00 €
50mg
1,857.00 €
Estimated delivery in United States, on Friday 29 Nov 2024

Product Information

Name:
(1R,2R)-Bortezomib
Synonyms:
  • Boronic acid
  • B-[(1R)-3-methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-
  • B-[(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid
  • bortezomib diastereomer (R,R) (USP)
  • bortezomib related compound A (USP)
Description:

Impurity Bortezomib USP Related Compound A
Applications (1R,2R)-Bortezomib is a diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009)

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
384.24
Formula:
C19H25BN4O4
Purity:
>85%
Color/Form:
Neat
InChI:
InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17+/m1/s1
InChI key:
InChIKey=GXJABQQUPOEUTA-LDCVWXEPSA-N
SMILES:
CC(C)CC(NC(=O)[C@@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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