Bosentan-d4

CAS: 1065472-77-6

Ref. TR-B675902

Product Information

• Name: Bosentan-d4
• Synonyms: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2’-bipyrimidin]-4-yl]benzenesulfonamide, p-tert-Butyl-N-[6-(2-hydroxyethoxy-d4)-5- (o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide, Actelion-d4, Ro 47-0203-d4, Ro 47-0203/039-d4, Tracleer-d4
• Brand: TRC
• Description: Applications Labelled Bosentan (B675900). A mixed endothelin receptor antagonist. Used as a vasodilator. Antihypertensive.References Clozel, M., et al.: J. Pharmacol. Exp. Ther., 270, 228 (1994), Gutsch, G., et al.: Cardiovasc. Drugs Ther., 10, 717 (1996), Weber, C., et al.: Clin Pharmacol. Ther., 60, 124 (1996), Krum, H., et al.: N. Engl. J. Med., 338, 784 (1998)

Chemical properties

• Molecular weight: 555.64
• Formula: C₂₇H₂₅D₄N₅O₆S
• Color/Form: Neat
• InChI: InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)/i16D2,17D2
• InChI key: InChIKey=GJPICJJJRGTNOD-RZOBCMOLSA-N
• SMILES: [2H]C([2H])(O)C([2H])([2H])Oc1nc(-c2ncccn2)nc(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c1Oc1ccccc1OC