8R-Brassicasterol

Ref. TR-B676853

Product Information

• Name: 8R-Brassicasterol
• Synonyms: (3S,8R,9S,10R,13R,14S,17R)-17-((2R,5R,E)-5,6-Dimethylhept-3-en-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
• Brand: TRC
• Description: Applications 8R-Brassicasterol is a by-product in the synthesis of Brassicasterol (B676850). Brassicasterol is a phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. This compound has been shown to inhibit sterol Δ24-reductase, an enzyme involved in the mammalian cholesterol biosynthesis pathway.References Bishop, G.J., et al.: Plant Cell Physiol. 42, 114, (2001); Fernandez, C., et al., Biochem. J. 366, 109 (2002)

Chemical properties

• Molecular weight: 398.664
• Formula: C₂₈H₄₆O
• Color/Form: Neat
• InChI: InChI=1S/C28H46O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-9,18-20,22-26,29H,10-17H2,1-6H3/b8-7+/t19-,20+,22-,23+,24+,25-,26-,27-,28+/m0/s1
• InChI key: InChIKey=OILXMJHPFNGGTO-BCQFNOCSSA-N
• SMILES: CC(C)[C@@H](C)/C=C/[C@@H](C)[C@H]1CC[C@H]2[C@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C