Bretylium Tosylate

CAS: 61-75-6

Ref. TR-B677370

Product Information

• Name: Bretylium Tosylate
• Synonyms: Benzenemethanaminium, 2-bromo-N-ethyl-N,N-dimethyl-, 4-methylbenzenesulfonate (1:1), (o-Bromobenzyl)ethyldimethylammonium p-toluenesulfonate (6CI,7CI), Ammonium, (o-bromobenzyl)ethyldimethyl-, p-toluenesulfonate (8CI), Benzenemethanaminium, 2-bromo-N-ethyl-N,N-dimethyl-, salt with 4-methylbenzenesulfonic acid (1:1) (9CI), ASL 603, Bretylan, Bretylate, Bretylium p-toluenesulfonate, Bretylium tosilate, Bretylol, Darenthin, N-Ethyl-N-(o-bromobenzyl)-N,N-dimethylammonium tosylate, NSC 62164, Ornid, (2-Bromophenyl)Methyl-Ethyl-Dimethyl-Ammonium, (o-Bromobenzyl)ethyldimethylammonium p-toluenesulfonate, 2-Bromobenzylethyldimethylammonium Toluene-4-Sulphonate, 4-Methylbenzenesulfonic Acid, Ammonium, (o-bromobenzyl)ethyldimethyl-, p-toluenesulfonate, Asl 603, Benzenemethanaminium, 2-bromo-N-ethyl-N,N-dimethyl-, 4-methylbenzenesulfonate (1:1), Benzenemethanaminium, 2-bromo-N-ethyl-N,N-dimethyl-, salt with 4-methylbenzenesulfonic acid (1:1), Bretylium Tosilate, N-(2-bromobenzyl)-N,N-dimethylethanaminium 4-methylbenzenesulfonate, N-(4-bromobenzyl)-N,N-dimethylethanaminium 4-methylbenzenesulfonate
• CAS: 61-75-6

Description

Applications Bretylium tosylate has a biphasic response, initially inducing norepinephrine release followed by sympathetic ganglionic blockade. Bretylium tosylate is a class III antiarrhythmic agent and a competitive inhibitor of acetylcholinesterase.
References Kuntzman, R., et al.: Clin. Pharmacol. Ther., 11, 829 (1970), Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Carter, J.E., et al.: Anal. Profiles Drug Subs., 9, 71 (1980),

• Brand: TRC

Chemical properties

• Molecular weight: 414.36
• Formula: C₁₈H₂₄BrNO₃S
• Color/Form: Neat
• InChI: /p-1, 1-6-2-4-7(5-3-6)11(8,9)10/h5-8H,4,9H2,1-3H3, 2-5H,1H3,(H,8,9,10)/q+1, InChI=1S/C11H17BrN.C7H8O3S/c1-4-13(2,3)9-10-7-5-6-8-11(10)12
• SMILES: CC[N+](C)(C)Cc1ccccc1Br.Cc1ccc(S(=O)(=O)[O-])cc1