Estimated delivery in United States, on Tuesday 18 Feb 2025
Product Information
Name:
Brivanib Alaninate
Controlled Product
Synonyms:
- [(2R)-1-[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxypropan-2-yl] (2S)-2-aminopropanoate
- (1R)-2-((4-((4-Fluoro-2-methyl-1H-indol-5-yl)oxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl)oxy)-1-methylethyl L-alanine ester
- <span class="text-smallcaps">L</span>-Alanine, (1R)-2-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-1-methylethyl ester
- Bms 582664
- Bms582664
- Brivanib alaninate
Description:
Applications A novel prodrug of dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 kinase inhibitor. Antitumor agent.
References Ellis, L., et al.: Eur. J. Cancer, 32A, 2451 (1996), Klagsbrun, M., et al.: Chem. Biol., 6, R217 (1999), Auguste, P., et al.: Cancer Res., 61, 1717 (2001), Bhide, R., et al.: J. Med. Chem., 49, 2143 (2006),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
441.455
Formula:
C22H24FN5O4
Color/Form:
Neat
InChI:
InChI=1S/C22H24FN5O4/c1-11-7-15-16(27-11)5-6-17(19(15)23)32-21-20-13(3)18(8-28(20)26-10-25-21)30-9-12(2)31-22(29)14(4)24/h5-8,10,12,14,27H,9,24H2,1-4H3/t12-,14+/m1/s1
InChI key:
InChIKey=LTEJRLHKIYCEOX-OCCSQVGLSA-N
SMILES:
Cc1cc2c(F)c(Oc3ncnn4cc(OC[C@@H](C)OC(=O)[C@H](C)N)c(C)c34)ccc2[nH]1
MDL:
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Technical inquiry about: TR-B677640 Brivanib Alaninate
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