Product Information
Name:Brivanib Alaninate
Controlled Product
Synonyms:
- L-Alanine (1R)-2-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo [2,1-f][1,2,4]triazin-6-yl]oxy]-1-methylethyl Ester
- BMS 582664
Brand:TRC
Description:Applications A novel prodrug of dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 kinase inhibitor. Antitumor agent.References Ellis, L., et al.: Eur. J. Cancer, 32A, 2451 (1996), Klagsbrun, M., et al.: Chem. Biol., 6, R217 (1999), Auguste, P., et al.: Cancer Res., 61, 1717 (2001), Bhide, R., et al.: J. Med. Chem., 49, 2143 (2006),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:441.455
Formula:C22H24FN5O4
Color/Form:Neat
InChI:InChI=1S/C22H24FN5O4/c1-11-7-15-16(27-11)5-6-17(19(15)23)32-21-20-13(3)18(8-28(20)26-10-25-21)30-9-12(2)31-22(29)14(4)24/h5-8,10,12,14,27H,9,24H2,1-4H3/t12-,14+/m1/s1
InChI key:InChIKey=LTEJRLHKIYCEOX-OCCSQVGLSA-N
SMILES:Cc1cc2c(F)c(Oc3ncnn4cc(OC[C@@H](C)OC(=O)[C@H](C)N)c(C)c34)ccc2[nH]1
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