(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran

CAS: 915095-89-5

Ref. TR-B680755

Product Information

• Name: (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran
• Synonyms: (S)-3-(4-(5-Bromo-2-chlorobenzyl)phenoxy)tetrahydrofuran,Furan, 3-[4-[(5-bromo-2-chlorophenyl)methyl]phenoxy]tetrahydro-, (3S)- (9CI, ACI), (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran (ACI), (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]oxolane, (S)-4-Bromo-1-chloro-2-(4-tetrahydrofuran-3-yloxy-benzyl)-benzene, Empagliflozin Impurity I, (S)-3-(4-(5-Bromo-2-chlorobenzyl)phenoxy)tetrahydrofuran
• Brand: TRC
• Description: Applications (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran is used as a reactant in the efficient synthesis of empagliflozin inhibitor of SGLT-2 utilizing AlCl3-promoted silane reduction of β-glycopyranoside.References Wang, X., et al.: Org. Lett., 16, 4090 (2014)

Chemical properties

• Molecular weight: 367.66
• Formula: C₁₇H₁₆BrClO₂
• Color/Form: Off-White
• InChI: InChI=1S/C17H16BrClO2/c18-14-3-6-17(19)13(10-14)9-12-1-4-15(5-2-12)21-16-7-8-20-11-16/h1-6,10,16H,7-9,11H2/t16-/m0/s1
• InChI key: InChIKey=HUNLNKBDQXGMAP-INIZCTEOSA-N
• SMILES: Clc1ccc(Br)cc1Cc1ccc(O[C@H]2CCOC2)cc1