2-Bromo α-Ergocryptine Mesylate

CAS: 22260-51-1

Ref. TR-B682600

Product Information

• Name: 2-Bromo α-Ergocryptine Mesylate
• Synonyms: Bromocriptine mesilate, (6aR,9R)-5-Bromo-N-[(2R,5S,10aS,10bS)-10b-hydroxy-2-(1-methylethyl)-5-(2-methylpropyl)-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide monomethanesulfonate, Ergocryptine, 2-bromo-, monomethanesulfonate (salt) (8CI), 8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine, ergotaman-3',6',18-trione deriv., Indolo[4,3-fg]quinoline, ergotaman-3',6',18-trione deriv., (+)-Bromocriptine methanesulfonate, Bagren, Bromocriptine mesylate, Bromocriptine methanesulfonate, Bromocryptine mesylate, Bromocryptine methanesulfonate, CB 154, Cycloset, Parlodel, Pravidel, Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (5α)-, methanesulfonate (1:1), Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (5'α)-
• Brand: TRC

Description

Applications The dopamine receptors play important role in cognition, memory, learning, and motor control (1). These receptors have been implicated as a therapeutic target for many psychiatric and neurological disorders. 2-Bromo-α-Ergocryptine is a dopamine receptor agonist and a derivative of the ergotoxin group of ergot alkaloids (2). It is also a prolactin inhibitor (3).
References (1) Ptácek, R., et al.: Med Sci Monit. 17, RA215 (2011) (2) Lieberman, A. N. and Goldstein, M.: Pharmacol Rev. 37, 217 (1985) (3) Nazli, K., et al.: Br J Clin Pract. 43, 322 (1989)

Chemical properties

• Molecular weight: 750.7
• Formula: C₃₂H₄₀BrN₅O₅·CH₄O₃S
• Color/Form: Neat
• InChI: InChI=1S/C32H40BrN5O5.CH4O3S/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18;1-5(2,3)4/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39);1H3,(H,2,3,4)/t18-,23-,24+,25+,31-,32+;/m1./s1
• InChI key: InChIKey=NOJMTMIRQRDZMT-GSPXQYRGSA-N
• SMILES: CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](NC(=O)[C@@H]3C=C4c5cccc6[nH]c(Br)c(c56)C[C@H]4N(C)C3)(C(C)C)C(=O)N12.CS(=O)(=O)O