(11β,16α)-9-Bromo-21-[(ethoxycarbonyl)oxy]-11-(formyloxy)-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione

CAS: 192447-02-2

Ref. TR-B683236

Product Information

• Name: (11β,16α)-9-Bromo-21-[(ethoxycarbonyl)oxy]-11-(formyloxy)-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione
• Synonyms: Pregna-1,4-diene-3,20-dione, 9-bromo-21-[(ethoxycarbonyl)oxy]-11-(formyloxy)-17-hydroxy-16-methyl-, (11β,16α)- (9CI), Dexamethasone impurity 11
• Brand: TRC
• Description: Stability Moisture SensitiveApplications (11β,16α)-9-Bromo-21-[(ethoxycarbonyl)oxy]-11-(formyloxy)-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione is an impurity of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent.References Spangler, M., et al.: Chromatographia, 54(5/6), 329-334 (2001);Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995)

Chemical properties

• Molecular weight: 553.44
• Formula: C₂₆H₃₃BrO₈
• Color/Form: Neat
• InChI: InChI=1S/C26H33BrO8/c1-5-33-22(31)34-13-20(30)26(32)15(2)10-19-18-7-6-16-11-17(29)8-9-23(16,3)25(18,27)21(35-14-28)12-24(19,26)4/h8-9,11,14-15,18-19,21,32H,5-7,10,12-13H2,1-4H3/t15-,18+,19+,21+,23+,24+,25+,26+/m1/s1
• InChI key: InChIKey=CPTOBXRMWWTWQM-FEEFRVHUSA-N
• SMILES: CCOC(=O)OCC(=O)[C@@]1(O)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Br)[C@@H](OC=O)C[C@@]21C