N-(2-Bromoethyl-d4)phthalimide

CAS: 1009307-39-4

Ref. TR-B683977

Product Information

• Name: N-(2-Bromoethyl-d4)phthalimide
• Synonyms: 2-(2-Bromoethyl-1,1,2,2-d4)-1H-isoindole-1,3(2H)-dione

Description

Applications N-(2-Bromoethyl-d4)phthalimide is the labeled analogue of N-(2-Bromoethyl)phthalimide (B683975), a building block that has been used as a reactant for the preparation of β-Cyclodextrin derivatives. N-(2-Bromoethyl-d4)phthalimide is an intermediate in the synthesis of (E)-Fluvoxamine-d4 Maleate (F603503), the labeled analogue of (E)-Fluvoxamine Maleate (F603500), a selective serotonin reuptake inhibitor (SSRI) used as an anti-depressant. Antiobsessional.
References Karginov, V.A., et. al.: Bioorg. Med. Chem., 14, 33 (2006); Claassen, V., et al.: Br. J. Pharmacol., 60, 505 (1977); Koran, L.M., et al.: J. Clin. Psychopharmacol., 16, 121 (1996); Ware, M.R., et al.: J. Clin. Psychiatry, 58, Suppl. 5, 15 (1997); Inazu, M., et al.: Neurochem. Int., 39, 39 (2001)

• Brand: TRC

Chemical properties

• Molecular weight: 258.1
• Formula: C₁₀H₄D₄BrNO₂
• Color/Form: Neat
• InChI: InChI=1S/C10H8BrNO2/c11-5-6-12-9(13)7-3-1-2-4-8(7)10(12)14/h1-4H,5-6H2/i5D2,6D2
• InChI key: InChIKey=CHZXTOCAICMPQR-NZLXMSDQSA-N
• SMILES: [2H]C([2H])(Br)C([2H])([2H])N1C(=O)c2ccccc2C1=O