2-Bromophenylacetic Acid

CAS: 18698-97-0

Ref. TR-B687905

Product Information

• Name: 2-Bromophenylacetic Acid
• Synonyms: 2-Bromobenzeneacetic Acid, o-Bromophenylacetic Acid, (2-Bromophenyl)Acetate, -Rarechem Al Bo 0109, 2-(2-Bromophenyl)acetic acid, 2-Bromobenzeneacetic acid, 2-Bromophenylacetic acid, 98+%, Acetic acid, (o-bromophenyl)-, Benzeneacetic acid, 2-bromo-, Labotest-Bb Lt00454446, O-Bromophenylacetic Acid, Timtec-Bb Sbb006626

Description

Applications 2-Bromophenylacetic Acid is used as the starting material in the synthesis of 2,3,3a,12b-Tetradehydro Asenapine (T291630); a degredation product of Asenapine (A788000) which is a combined serotonin (5HT2) and dopamine (D2) receptor antagonist structurally related to Mianserin (M341500, HCl). Also used as an antipsychotic.
References Meltzer, H., et al.: J. Pharmacol. Exp. Ther., 251, 238 (1989); Schotte, A., et al.: Brain Res., 631, 191 (1993); Andree, B., et al.: Psychopharmacology, 131, 339 (1997); Richelson, E., et al.: Life Sci., 68, 29 (2000)

• Brand: TRC

Chemical properties

• Molecular weight: 215.04
• Formula: C₈H₇BrO₂
• Color/Form: Neat
• InChI: InChI=1S/C8H7BrO2/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4H,5H2,(H,10,11)
• InChI key: InChIKey=DWXSYDKEWORWBT-UHFFFAOYSA-N
• SMILES: O=C(O)Cc1ccccc1Br