2-(Bromomethyl)benzonitrile

CAS: 22115-41-9

Ref. TR-B687970

Product Information

• Name: 2-(Bromomethyl)benzonitrile
• Synonyms: alpha-Bromo-o-tolunitrile, (2-Cyanophenyl)methyl Bromide, 1-(Bromomethyl)-2-cyanobenzene, 2-Cyano-a-bromotoluene, 2-Cyanobenzyl Bromide, o-(Bromomethyl)benzonitrile, o-Cyanobenzyl bromide, alpha-Bromo-2-cyanotoluene, alpha-Bromo-otolunitrile,alpha-Bromo-o-toluonitrile, (2-Cyanophenyl)methyl bromide, 2-Cyanide Benzyl Bromide, 2-Cyano-α-bromotoluene, 2-Cyanobenzyl bromide, 2-Nitrilebenzyl bromide, Alpha-Bromo-O-Toluonitrile, Alpha-Bromo-Ortho-Tolunitrile, Benzonitrile, 2-(bromomethyl)-, O-Cyanobenzyl bromide, o-Tolunitrile, α-bromo-, α-Bromo-2-cyanotoluene, α-Bromo-o-tolunitrile, α-Bromo-o-toluonitrile

Description

Applications 2-(Bromomethyl)benzonitrile is an intermediate in the synthesis of Alogliptin (A575425), an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Antidiabetic agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lai, Z., et. al.: Eur. J. Med. Chem., 83, 547 (2014); Lynn, F., et al.: Diabetes, 50, 1004 (2001); Trumper, A., et al.: J. Endocrinol., 174, 233 (2002); Vollmer, K., et al.: J. Clin. Endocrinol. Metab., 94, 1379 (2009)

• Brand: TRC

Chemical properties

• Molecular weight: 196.04
• Formula: C₈H₆BrN
• Color/Form: Neat
• SMILES: N#Cc1ccccc1CBr