Bufalin

CAS: 465-21-4

Ref. TR-B689510

Product Information

• Name: Bufalin
• Synonyms: 5-[(3S,5R,8R,9S,10S,13R,14R,17S)-3,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pyran-2-one, (3Beta,5Beta,8Xi,9Xi)-3,14-Dihydroxybufa-20,22-Dienolide, (3β,5β)-3,14-Dihydroxybufa-20,22-dienolide, 3,14-Dihydroxybufa-20,22-Dienolide, 5β-Bufa-20,22-dienolide, 3β,14-dihydroxy-, B 0261, Bufa-20,22-dienolide, 3,14-dihydroxy-, (3β,5β)-, NSC 89595

Description

Applications A bufadienolide derivative, cardiac steroid, a component of bufadienolides present in the traditional Chinese medicine Chan'su, used therapeutically for the treatment of heart disease, also has been reported as a protective factor in many tumors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wang, B., et al.: Biol. Pharm. Bull., 34, 967 (2011), Song, C., et al.: Xiandai Zhongliu Yixue, 18, 1863, 2010.

• Brand: TRC

Chemical properties

• Molecular weight: 386.52
• Formula: C₂₄H₃₄O₄
• Color/Form: Neat
• InChI: InChI=1S/C24H34O4/c1-22-10-7-17(25)13-16(22)4-5-20-19(22)8-11-23(2)18(9-12-24(20,23)27)15-3-6-21(26)28-14-15/h3,6,14,16-20,25,27H,4-5,7-13H2,1-2H3/t16-,17+,18+,19+,20-,22+,23-,24-/m1/s1
• InChI key: InChIKey=QEEBRPGZBVVINN-BMPKRDENSA-N
• SMILES: C[C@]12CC[C@H](O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](c3ccc(=O)oc3)CC[C@]12O