Buphenin Hydrochloride(Mixture of Diastereomers)

CAS: 849-55-8

Ref. TR-B689645

Product Information

• Name: Buphenin Hydrochloride(Mixture of Diastereomers)
• Synonyms: Buphenine Hydrochloride, Nylidrin hydrochloride, Arlidin, Arlidin hydrochloride, Bufedon, Buphedrin, Buphenin hydrochloride, Buphenine hydrochloride, Dilatal, Dilatol, Dilatol hydrochloride, Dilatropon, Dilydrin, NSC 142004, Nylidrine hydrochloride, Opino, Penitardon, Perdilatal, RHC 3432A, Rudilin, Rydrin, SKF 1700A, Suprifen Psb hydrochloride, Tocodilydrin, Tocodrin, Verina, 4-Hydroxy-α-[1-[(1-methyl-3-phenylpropyl)amino]ethyl]benzenemethanol hydrochloride, (±)-Nylidrin hydrochloride
• Brand: TRC

Description

Applications Buphenin (Nylidrin), is shown to be an effective inhibitor of IgE-mediated release of histamine from human basophils, and thus can be used as antiallergic agent. It is also one of the FDA approved drug as Inhibitors of the Human Sodium Taurocholate Cotransporting Polypeptide (NTCP).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Khandwala, A., et al.: Internatio. Arch. Allergy Applied Immunology, 70 (4), 295 (1983); Dong, Zh., Mol. Pharma., 10 (3), 1008 (2013);

Chemical properties

• Molecular weight: 335.87
• Formula: C₁₉H₂₅NO₂·ClH
• Color/Form: Neat
• InChI: InChI=1S/C19H25NO2.ClH/c1-14(8-9-16-6-4-3-5-7-16)20-15(2)19(22)17-10-12-18(21)13-11-17;/h3-7,10-15,19-22H,8-9H2,1-2H3;1H
• InChI key: InChIKey=CLJHABUMMDMAFA-UHFFFAOYSA-N
• SMILES: CC(CCc1ccccc1)NC(C)C(O)c1ccc(O)cc1.Cl