Bupranolol

CAS: 14556-46-8

Ref. TR-B689650

Product Information

• Name: Bupranolol
• Synonyms: 2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-, 2-Propanol, 1-(tert-butylamino)-3-[(6-chloro-m-tolyl)oxy]- (8CI), 1-(2-Chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-2-propanol, Bupranol, Ophtorenin, 1-(Tert-Butylamino)-3-(2-Chloro-5-Methylphenoxy)Propan-2-Ol, 1-(tert-Butylamino)-3-((6-chloro-m-tolyl)-oxy)-2-propanol, 1-t-Butylamino-3-(2-chloro-5-methylphenoxy) -2-propanol, 2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-((1,1-dimethylethyl)amino)-, 2-Propanol, 1-(tert-butylamino)-3-((6-chloro-m-tolyl)oxy)- (8CI), 2-Propanol, 1-(tert-butylamino)-3-(2-chloro-5-methylphenoxy)-, 2-Propanol, 1-(tert-butylamino)-3-(6-chloro-m-tolyloxy)-, 2-Propanol, 1-(tert-butylamino)-3-[(6-chloro-m-tolyl)oxy]-, 3-(tert-Butylamino)-1-(6-chloro-m-tolyloxy)-2-propanol, Brn 2272923, Bupranolol [INN:DCF], Bupranololum, Bupranololum [INN-Latin], Kl 255, Sk&F 16805-A, Unii-858Ygi5Pit

Description

Applications Bupranolol is an antagonist at the cardiostimulatory low-affinity state of b(1)-adrenoceptors and is known to treat hypertension and tachycardia.
References Zelaszczyk, D., et al.: J. Physiol. Pharmacol., 60, 51 (2009); Wachter, W., et al.: Naunyn. Schmiedebergs. Arch. Pharmacol., 313, 1 (1980);

• Brand: TRC

Chemical properties

• Molecular weight: 271.78
• Formula: C₁₄H₂₂ClNO₂
• Color/Form: Neat
• InChI: InChI=1S/C14H22ClNO2/c1-10-5-6-12(15)13(7-10)18-9-11(17)8-16-14(2,3)4/h5-7,11,16-17H,8-9H2,1-4H3
• InChI key: InChIKey=HQIRNZOQPUAHHV-UHFFFAOYSA-N
• SMILES: Cc1ccc(Cl)c(OCC(O)CNC(C)(C)C)c1