t-Butylnorsynephrine

CAS: 96948-64-0

Ref. TR-B690810

Product Information

• Name: t-Butylnorsynephrine
• Synonyms: Salbutamol Sulphate Imp. B (EP), Salbutamol Imp. B (EP), (1RS)-2-[(1,1-Dimethylethyl)amino]-1-(4-hydroxyphenyl)ethanol, Salbutamol Impurity B, Salbutamol Sulfate Impurity B, Salbutamol Impurity B, Benzenemethanol, alpha-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-, (+-)-, Benzenemethanol, α-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, Buctopamine, Kwd 2066, α-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxybenzenemethanol

Description

Impurity Salbutamol EP Impurity B
Applications t-Butylnorsynephrine (Salbutamol EP Impurity B) is a derivative of norsynephrine, an endogenous biogenic amine that is closely related to norepinephrine, which has effects on the adrenergic and dopaminergic system. Structure and activity tudies have shown that t-Butylnorsynephrine may also exhibit effects towards β-adrenergic receptors and β-adrenergic receptor-coupled adenylate cyclase.
References Wong, A., et al.: Molec. Pharmacol., 31, 368 (1987); Constanzi, S., et al.: J. Comp. Chem., 33, 561, (2012);

• Brand: TRC

Chemical properties

• Molecular weight: 209.28
• Formula: C₁₂H₁₉NO₂
• Color/Form: Yellow
• InChI: InChI=1S/C12H19NO2/c1-12(2,3)13-8-11(15)9-4-6-10(14)7-5-9/h4-7,11,13-15H,8H2,1-3H3
• InChI key: InChIKey=JOGFUYPGDLRKHD-UHFFFAOYSA-N
• SMILES: CC(C)(C)NCC(O)c1ccc(O)cc1