N-Butyldeoxynojirimycin Hydrochloride

CAS: 210110-90-0

Ref. TR-B691000

Product Information

• Name: N-Butyldeoxynojirimycin Hydrochloride
• Synonyms: 3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride (1:1), (2R,3R,4R,5S)-, 3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R,5S)- (9CI), Miglustat hydrochloride, 3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride (1:1), (2R,3R,4R,5S)-, 3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R,5S)-, Miglustat HCl

Description

Applications An inhibitor of a-glucosidase 1 as well as being an inhibitor of HIV cytopathicity. N-Butyldeoxynojirimycin has recently been used to retard lipid storage in the central nervous system of an animal model of Tay-Sachs disease.1-Deoxynojirimycin derivatives as selective inhibitors of glucosylceramide metabolism in man.
References Hettkamp, H., et al.: Eur. J. Biochem., 142, 85 (1984), Szumilo, T., et al.: Arch. Biochem. Biophys., 247, 261 (1986), Fleet, G.W.J., et al.: FEBS Letters, 237, Number 1,2, 128 (1988), Kolter, T., et al.: Angew. Chem. Int. Ed. Engl., 36, 1955 (1997),

• Brand: TRC

Chemical properties

• Molecular weight: 255.74
• Formula: C₁₀H₂₁NO₄·ClH
• Color/Form: Off-White
• InChI: InChI=1S/C10H21NO4.ClH/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12;/h7-10,12-15H,2-6H2,1H3;1H/t7-,8+,9-,10-;/m1./s1
• InChI key: InChIKey=QPAFAUYWVZMWPR-ZSOUGHPYSA-N
• SMILES: CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO.Cl