tert-Butyl (S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate

CAS: 69610-40-8

Ref. TR-B692205

Product Information

• Name: tert-Butyl (S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
• Synonyms: (2S)-2-(Hydroxymethyl)-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester, (2S)-1-(tert-Butoxycarbonyl)-2-pyrrolidinemethanol, (2S)-2-Hydroxymethylpyrrolidine-1-carboxylic Acid tert-butyl Ester, (2S)-Hydroxymethylpyrrolidine-1-carboxylic Acid tert-butyl Ester, (S)-(+)-N-Boc-prolinol, (S)-(-)-1-(tert-Butoxycarbonyl)-2-pyrrolidinemethanol, (S)-1-(tert-Butoxycarbonyl)-2-pyrrolidinemethanol, (S)-1-BOC-2-Pyrrolidinemethanol, (S)-tert-Butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate, 1,1-Dimethylethyl (2S)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate, 1-BOC-2-(S)-Pyrrolidinemethanol, BOC-L-prolinol, Boc-(S)-(-)-2-pyrrolidinemethanol, N-Boc-L-prolinol, N-[(tert-Butoxy)carbonyl]-L-prolinol, N-tert-Butoxycarbonyl-(2S)-2-pyrrolidinemethanol, tert-Butyl (2S)-2-(Hydroxymethyl)-1-pyrrolidinecarboxylate, tert-Butyl (2S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
• Brand: TRC
• Description: Applications tert-Butyl (S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate, is a building block used foe the synthesis of novel nicotinic acetylcholine receptor ligands with cognition-enhancing properties. It can also be used in the synthesis of chiral β-amino sulfides and β-amino thiols.References Elliiot, R. L., et al.: Bioorg. Med. Chem. Lett., 6, 2283 (1996); Abreo, M. A., et al.: J. Med. Chem., 39(4), 817 (1996)

Chemical properties

• Molecular weight: 201.26
• Formula: C₁₀H₁₉NO₃
• Color/Form: Neat
• InChI: InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-5-8(11)7-12/h8,12H,4-7H2,1-3H3/t8-/m0/s1
• InChI key: InChIKey=BFFLLBPMZCIGRM-QMMMGPOBSA-N
• SMILES: CC(C)(C)OC(=O)N1CCC[C@H]1CO