tert-Butyl (R)-3-Aminopiperidine-1-carboxylate

CAS: 188111-79-7

Ref. TR-B692215

Product Information

• Name: tert-Butyl (R)-3-Aminopiperidine-1-carboxylate
• Synonyms: (3R)-3-Amino-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester, (R)-1-tert-Butoxycarbonyl-3-aminopiperidine, (R)-3-Amino-1-Boc-piperidine, (R)-3-Aminopiperidine-1-carboxylic Acid tert-Butyl Ester, (R)-1-tert-Butoxycarbonyl-3-aminopiperidine, (R)-3-Aminopiperidine-1-carboxylic Acid tert-Butyl Ester
• Brand: TRC

Description

Applications tert-Butyl (R)-3-Aminopiperidine-1-carboxylate, is an heterocyclic building block used for the synthesis of more complex pharmaceutical compounds. It is also found to act as a γ-secretase modulators, and a potent structure for lowering Aβ42 production in both in vitro and in vivo.
References Kobayashi, T., et al.: Bioorg. Med. Chem. Lett., 24, 378 (2014);

Chemical properties

• Molecular weight: 200.28
• Formula: C₁₀H₂₀N₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
• InChI key: InChIKey=AKQXKEBCONUWCL-MRVPVSSYSA-N
• SMILES: CC(C)(C)OC(=O)N1CCC[C@@H](N)C1