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Product Information
Name:
tert-Butoxycarbonyl-D-proline
Controlled Product
Synonyms:
- (2R)-1,2-Pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester
- (R)-1,2-Pyrrolidinedicarboxylic acid
- 1-(1,1-dimethylethyl) ester
- (2R)-1-tert-Butoxycarbonylpyrrolidine-2-carboxylic acid
- (R)-1-(tert-Butyloxycarbonyl)pyrrolidine-2-carboxylic acid
- (R)-1-tert-Butoxycarbonylpyrrolidine-2-carboxylic acid
- (R)-2-Carboxypyrrolidine-1-carboxylic acid tert-butyl ester
- (R)-Pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
- 1-tert-Butoxycarbonyl-D-proline
- 1-tert-Butyl (R)-pyrrolidine-1,2-dicarboxylate
- See more synonyms
- N-(tert-Butoxycarbonyl)-(R)-proline
- N-BOC-D-proline
- N-tert-Butoxycarbonyl-D-proline
- NSC 334360
- (2R)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylate
- 1-Boc-D-proline
- Boc-D-Pro-OH
- Boc-D-proline
CAS:
Description:
Applications tert-Butoxycarbonyl-D-proline is Boc protected D-proline (P755990). It is used to prepare trichostatin A and trapoxin B analogs as histone deacetylase inhibitors. It is also used to prepare potent and selective nonpeptide inhibitors of caspases 3 and 7.
References Jung, M., et al.: Bioorg. Med. Chem. Lett., 7, 1655 (1997); Lee, D., et al.: J. Med. Chem,, 44, 2015 (2001)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
215.25
Formula:
C10H17NO4
Color/Form:
Off-White Solid
InChI:
InChI=1S/C10H17NO4/c1-10(2,3)15-9(14)11-6-4-5-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)/t7-/m1/s1
InChI key:
InChIKey=ZQEBQGAAWMOMAI-SSDOTTSWSA-N
SMILES:
CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)O
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-B692535 tert-Butoxycarbonyl-D-proline
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