tert-Butoxycarbonyl-D-proline

CAS: 37784-17-1

Ref. TR-B692535

Product Information

• Name: tert-Butoxycarbonyl-D-proline
• Synonyms: (2R)-1,2-Pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester, (R)-1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2R)-1-tert-Butoxycarbonylpyrrolidine-2-carboxylic acid, (R)-1-(tert-Butyloxycarbonyl)pyrrolidine-2-carboxylic acid, (R)-1-tert-Butoxycarbonylpyrrolidine-2-carboxylic acid, (R)-2-Carboxypyrrolidine-1-carboxylic acid tert-butyl ester, (R)-Pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester, 1-tert-Butoxycarbonyl-D-proline, 1-tert-Butyl (R)-pyrrolidine-1,2-dicarboxylate, N-(tert-Butoxycarbonyl)-(R)-proline, N-BOC-D-proline, N-tert-Butoxycarbonyl-D-proline
• Brand: TRC
• Description: Applications tert-Butoxycarbonyl-D-proline is Boc protected D-proline (P755990). It is used to prepare trichostatin A and trapoxin B analogs as histone deacetylase inhibitors. It is also used to prepare potent and selective nonpeptide inhibitors of caspases 3 and 7.References Jung, M., et al.: Bioorg. Med. Chem. Lett., 7, 1655 (1997); Lee, D., et al.: J. Med. Chem,, 44, 2015 (2001)

Chemical properties

• Molecular weight: 215.25
• Formula: C₁₀H₁₇NO₄
• Color/Form: Neat
• InChI: InChI=1S/C10H17NO4/c1-10(2,3)15-9(14)11-6-4-5-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)/t7-/m1/s1
• InChI key: InChIKey=ZQEBQGAAWMOMAI-SSDOTTSWSA-N
• SMILES: CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)O