(1r,4r)-4-((2-(Butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-yl)amino)cyclohexanol
CAS: 1493694-70-4
Ref. TR-B692540
| 5mg | 179.00 € | ||
| 50mg | 977.00 € | ||
| 250mg | 3,516.00 € |
Estimated delivery in United States, on Tuesday 25 Jun 2024
Product Information
Name:
(1r,4r)-4-((2-(Butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-yl)amino)cyclohexanol
Controlled Product
Synonyms:
- trans-4-[[2-(Butylamino)-5-[5-(4-morpholinylmethyl)-2-pyridinyl]-4-pyrimidinyl]amino]cyclohexanol
- UNC2250
CAS:
Description:
Applications (1r,4r)-4-((2-(Butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-yl)amino)cyclohexanol inhibits steady-state phosphorylation of endogenous Mer and blocks ligand-stimulated activation of a chimeric EGFR-Mer protein. (1r,4r)-4-((2-(Butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-yl)amino)cyclohexanol also decreases colony-forming potential in rhabdoid and NSCLC tumor cells.
References Zhang, W., et. al.: J. Med. Chem., 56, 9683 (2013)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
440.58
Formula:
C24H36N6O2
Color/Form:
Pale Yellow to Yellow Solid
InChI:
InChI=1S/C24H36N6O2/c1-2-3-10-25-24-27-16-21(23(29-24)28-19-5-7-20(31)8-6-19)22-9-4-18(15-26-22)17-30-11-13-32-14-12-30/h4,9,15-16,19-20,31H,2-3,5-8,10-14,17H2,1H3,(H2,25,27,28,29)/t19-,20-
InChI key:
InChIKey=HSYSSKFCQHXOBP-MXVIHJGJSA-N
SMILES:
CCCCNc1ncc(-c2ccc(CN3CCOCC3)cn2)c(N[C@H]2CC[C@H](O)CC2)n1
MDL:
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Density:
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EINECS:
Merck:
HS code:
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