1-(4-sec-Butylphenyl)ethanone

CAS: 7645-81-0

Ref. TR-B692715

Product Information

• Name: 1-(4-sec-Butylphenyl)ethanone
• Synonyms: 1-[4-(1-Methylpropyl)phenyl]-ethanone, 4'-sec-Butyl-acetophenone, 4-(2-Butyl)acetophenone, 4-sec-Butylacetophenone, p-sec-Butylacetophenone, 1-[4-(Butan-2-Yl)Phenyl]Ethan-1-One, Ethanone, 1-[4-(1-Methylpropyl)Phenyl]-

Description

Applications 1-(4-sec-Butylphenyl)ethanone is a useful synthetic intermediate in the synthesis of 2-(p-sec-Butylphenyl)propionic Acid (B692720); an impurity of Ibuprofen (I140000) which is a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.
References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)

• Brand: TRC

Chemical properties

• Molecular weight: 176.25
• Formula: C₁₂H₁₆O
• Color/Form: Neat
• InChI: InChI=1S/C12H16O/c1-4-9(2)11-5-7-12(8-6-11)10(3)13/h5-9H,4H2,1-3H3