2-(3-(tert-Butylamino)-2-hydroxypropyl)-4-morpholino-1,2,5-thiadiazol-3(2H)-one (>90%)

CAS: 158636-97-6

Ref. TR-B692940

Product Information

• Name: 2-(3-(tert-Butylamino)-2-hydroxypropyl)-4-morpholino-1,2,5-thiadiazol-3(2H)-one (>90%)
• Synonyms: Timolol Impurity H, 2-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropyl]-4-(4-morpholinyl)-1,2,5-thiadiazol-3(2H)-one
• Brand: TRC
• Description: Impurity Timolol EP Impurity HApplications 2-(3-(tert-Butylamino)-2-hydroxypropyl)-4-morpholino-1,2,5-thiadiazol-3(2H)-one is a impurity of Timolol (T443710), an antihypertensive; antiarrhythmic (class II); antianginal; antiglaucoma agent.References Lacroix, P.M., et. al.: Chirality, 6, 484 (1994); Wasson, et al.: J. Med. Chem., 15, 651 (1972); Franciosa, et al.: Clin. Pharmacol. Ther., 13, 138 (1972); Heel, R.C., et al.: Drugs, 17, 38 (1979); Rofman, B.A., et al.: Hypertension, 2, 643 (1980); Mazzo, D.J., et al.: Anal. Profiles Drug Subs., 16, 641 (1987)

Chemical properties

• Molecular weight: 316.42
• Formula: C₁₃H₂₄N₄O₃S
• Purity: >90%
• Color/Form: Neat
• InChI: InChI=1S/C13H24N4O3S/c1-13(2,3)14-8-10(18)9-17-12(19)11(15-21-17)16-4-6-20-7-5-16/h10,14,18H,4-9H2,1-3H3
• InChI key: InChIKey=NRTPOFNBMLVPDO-UHFFFAOYSA-N
• SMILES: CC(C)(C)NCC(O)Cn1snc(N2CCOCC2)c1=O