Buprenorphine 3-O-Methyl Ether

CAS: 16524-65-5

Ref. TR-B693430

Product Information

• Name: Buprenorphine 3-O-Methyl Ether
• Synonyms: (αS,5α,7α)-17-(Cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-α-methyl-6,14-ethenomorphinan-7-methanol, 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-α-methyl-, [5α,7α(S)]-, 6,14-endo-Ethanotetrahydrothebaine, 22-cyclopropyl-7α-(1-hydroxy-1,2,2-trimethylpropyl)- (8CI), 3-O-Methylbuprenorphine, Buprenorphine methyl ether, RX 6021M, (2S)-2-[17-(cyclopropylmethyl)-4,5α-epoxy-3,6-dimethoxy-6α,14-ethano-14α-morphinan-7α-yl]-3,3-dimethylbutan-2-ol (3-O-methylbuprenorphine), Buprenorphine Imp. D (EP)
• Brand: TRC
• Description: Applications Buprenorphine 3-O-Methyl Ether is an impurity of Buprenorphine (B689570), an analgesic that demonstrates narcotic agonist-antagonist properties.References Cami-Kobeci, G., et al.: J. Med. Chem., 54, 6531 (2011); Machara, A., et al.: Adv. Syn. Cata., 354, 613 (2012); Cowan, A., et al.: Adv. Biochem. Psychopharmacol., 8, 427 (1973)

Chemical properties

• Molecular weight: 481.67
• Formula: C₃₀H₄₃NO₄
• Color/Form: Neat
• InChI: InChI=1S/C30H43NO4/c1-26(2,3)27(4,32)21-16-28-11-12-30(21,34-6)25-29(28)13-14-31(17-18-7-8-18)22(28)15-19-9-10-20(33-5)24(35-25)23(19)29/h9-10,18,21-22,25,32H,7-8,11-17H2,1-6H3/t21-,22-,25-,27+,28-,29+,30?/m1/s1