Buprenorphine 3-O-Methyl-d3 Ether

CAS: 16524-65-5

Ref. TR-B693432

Product Information

• Name: Buprenorphine 3-O-Methyl-d3 Ether
• Synonyms: (αS,5α,7α)-17-(Cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-α-methyl-6,14-ethenomorphinan-7-methanol-d3, 22-Cyclopropyl-7α-(1-hydroxy-1,2,2-trimethylpropyl)-6,14-endo-ethanotetrahydrothebaine, Buprenorphine 3-O-methyl ether-d3, RX 6021M-d3, [5α,7α(S)]-17-(Cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-α-methyl-6,14-ethenomorphinan-7-methanol-d3
• Brand: TRC

Description

Applications Isotope labelled Buprenorphine 3-O-Methyl Ether is an impurity of Buprenorphine (B689570), an analgesic that demonstrates narcotic agonist-antagonist properties.
References Cami-Kobeci, G., et al.: J. Med. Chem., 54, 6531 (2011); Machara, A., et al.: Adv. Syn. Cata., 354, 613 (2012); Cowan, A., et al.: Adv. Biochem. Psychopharmacol., 8, 427 (1973);

Chemical properties

• Molecular weight: 484.685
• Formula: C₃₀D₃H₄₀NO₄
• Color/Form: Neat
• InChI: InChI=1S/C30H43NO4/c1-26(2,3)27(4,32)21-16-28-11-12-30(21,34-6)25-29(28)13-14-31(17-18-7-8-18)22(28)15-19-9-10-20(33-5)24(35-25)23(19)29/h9-10,18,21-22,25,32H,7-8,11-17H2,1-6H3/t21-,22-,25-,27?,28?,29+,30?/m1/s1/i5D3
• InChI key: InChIKey=TWUKPJNGRBWVGE-LYGNWHKHSA-N
• SMILES: [2H]C([2H])([2H])Oc1ccc2c3c1O[C@H]1C4(OC)CCC5(C[C@@H]4C(C)(O)C(C)(C)C)[C@@H](C2)N(CC2CC2)CC[C@]315