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4-Bromo-2-nitro-6-(trifluoromethyl)aniline

CAS:

Ref. TR-B699340

1g
110.00€
2500mg
245.00€
5g
412.00€
4-Bromo-2-nitro-6-(trifluoromethyl)aniline
TRC

Product Information

Name:4-Bromo-2-nitro-6-(trifluoromethyl)aniline
Controlled Product
Synonyms:
  • 4-Bromo-2-nitro-6-(trifluoromethyl)benzenamine
  • 2-Amino-5-bromo-3-nitrobenzotrifluoride
Brand:TRC
Description:

Applications 4-Bromo-2-nitro-6-(trifluoromethyl)aniline is a reagent for the preparation of 3-(5-arylbenzimidazol-2-yl)-1-oxa-2-azaspiro[4.5]decenes, a transient receptor potential melastatin 8 (TRPM8) antagonist for the treatment of painful conditions related to cold.
References Parks, D. J., et al.: J. Med. Chem., 54, 233-247 (2011);

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Chemical properties

Molecular weight:285.02
Formula:C7H4BrF3N2O2
Color/Form:Neat
InChI:InChI=1S/C7H4BrF3N2O2/c8-3-1-4(7(9,10)11)6(12)5(2-3)13(14)15/h1-2H,12H2
SMILES:Nc1c([N+](=O)[O-])cc(Br)cc1C(F)(F)F

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