(24R)-Calcipotriene

CAS: 112827-99-3

Ref. TR-C144220

Product Information

• Name: (24R)-Calcipotriene
• Synonyms: (5Z,7E,22E,24R)-24-cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1a,3ß,24-triol, 24-epi-calcipotriol), Calcipotriol Imp. D (EP), 1,3-Cyclohexanediol, 5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4R)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1S,3S,5Z)-, 9,10-Secochola-5,7,10(19),22-tetraene-1,3,24-triol, 24-cyclopropyl-, (1a,3ß,5Z,7E,22E,24R)- (9CI), (1S,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4R)-4-Cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol, 24R-Calcipotriol, PRI 2202

Description

Impurity Calcipotriol EP Impurity D
Applications (24R)-Calcipotriene (Calcipotriol EP Impurity D) is a synthetic analogs of vitamin D that was studied for its potential antitumor effects. Studies has shown the combined treatment with vitamin D analog (24R)-Calcipotriene was more effective than the treatment with cytostatics applied alone. (24R)-Calcipotriene is also the 24-R epimer of Calcipotriene (C144200).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wietrzyk, J., et al.: Anticancer. Res., 27, 3387 (2007); Tien, X.Y., et al.: Am. J. Physiol., 265, 143 (1993); Wietrzyk, J., et al.: Anti-Cancer. Drugs., 18, 447 (2007);

• Brand: TRC

Chemical properties

• Molecular weight: 412.605
• Formula: C₂₇H₄₀O₃
• Color/Form: Neat
• InChI: InChI=1S/C27H40O3/c1-17(6-13-25(29)20-8-9-20)23-11-12-24-19(5-4-14-27(23,24)3)7-10-21-15-22(28)16-26(30)18(21)2/h6-7,10,13,17,20,22-26,28-30H,2,4-5,8-9,11-12,14-16H2,1,3H3/b13-6+,19-7+,21-10-/t17-,22-,23-,24+,25+,26+,27-/m1/s1