6-Carboxyfluorescein-4',5'-bis(2,2,2-trifluoroacetato)-di Mercurate

CAS: 1036218-76-4

Ref. TR-C173665

Product Information

• Name: 6-Carboxyfluorescein-4',5'-bis(2,2,2-trifluoroacetato)-di Mercurate
• Synonyms: [6-carboxy-3',6'-dihydroxy-3-oxo-5'-[(2,2,2-trifluoroacetyl)oxymercurio]spiro[2-benzofuran-1,9'-xanthene]-4'-yl]-(2,2,2-trifluoroacetyl)oxymercury
• Brand: TRC
• Description: Applications 6-Carboxyfluorescein-4',5'-bis(2,2,2-trifluoroacetato)-di Mercurate is an intermediate in the synthesis of 4',5'-Bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic Acid(B431950) which is used as a probe able to bind efficiently and selectively to Cys-tagged proteins. The interaction with the protein is detected by an increase of the fluorescence emission of CrAsH.References Genin, E., et al.: J. Amer. Chem. Soc., 130, 8596 (2008); Gaspersic, J., et al: FEBS Journal, 2038 (2010)

Chemical properties

• Molecular weight: 1001.51
• Formula: C₂₅H₁₀F₆Hg₂O₁₁
• Color/Form: Neat
• InChI: InChI=1S/C21H10O7.2C2HF3O2.2Hg/c22-11-2-5-14-17(8-11)27-18-9-12(23)3-6-15(18)21(14)16-7-10(19(24)25)1-4-13(16)20(26)28-21;2*3-2(4,5)1(6)7;;/h1-7,22-23H,(H,24,25);2*(H,6,7);;/q;;;2*+1/p-2
• InChI key: InChIKey=NPOXAWIIQVUFHT-UHFFFAOYSA-L
• SMILES: O=C(O)c1ccc2c(c1)C1(OC2=O)c2ccc(O)c([Hg]OC(=O)C(F)(F)F)c2Oc2c1ccc(O)c2[Hg]OC(=O)C(F)(F)F