Estimated delivery in United States, on Friday 27 Dec 2024
Product Information
Name:
Canadine
Controlled Product
Synonyms:
- 6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine
- 5,8,13,13a-tetrahydro-9,10-dimethoxy-
- Berberine
- 9-deoxy-16,17-dihydro- (6CI)
- Berbine
- 9,10-dimethoxy-2,3-(methylenedioxy)- (7CI,8CI)
- Berberine
- tetrahydro-
- NSC 36351
- NSC 94918
- See more synonyms
- Tetrahydroberberine
- Tetrahydroumbellatine
- Xanthopuccine
- dl-Canadine
- dl-Tetrahydroberberine
- (+/-)-Tetrahydroberberine
- (±)-Tetrahydroberberine
- 5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine
- 6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 5,8,13,13a-tetrahydro-9,10-dimethoxy-
- Berberine, 9-deoxy-16,17-dihydro-
- Berberine, tetrahydro-
- Berbine, 9,10-dimethoxy-2,3-(methylenedioxy)-
- Tetrahydroberineper
Description:
Applications Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling.
References Duchowicz, P., et al.: Bioorg. Med. Chem., 14, 5876 (2006), Sun., et al.: Br. J. Pharmcol., 158, 1302 (2009), Deeb, O., et al.: Chem. Biol. Drug Des., 76, 255 (2010),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
339.38
Formula:
C20H21NO4
Color/Form:
Neat
InChI:
InChI=1S/C20H21NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,8-9,16H,5-7,10-11H2,1-2H3
InChI key:
InChIKey=VZTUIEROBZXUFA-UHFFFAOYSA-N
SMILES:
COc1ccc2c(c1OC)CN1CCc3cc4c(cc3C1C2)OCO4
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-C175175 Canadine
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