R-(+)-Carbidopa

CAS: 28875-92-5

Ref. TR-C175986

Product Information

• Name: R-(+)-Carbidopa
• Synonyms: Benzenepropanoic acid, a-hydrazinyl-3,4-dihydroxy-a-methyl-, (aR)-, Benzenepropanoic acid, a-hydrazino-3,4-dihydroxy-a-methyl-, (R)-, Benzenepropanoic acid, a-hydrazino-3,4-dihydroxy-a-methyl-, (aR)- (9CI), Hydrocinnamic acid, a-hydrazino-3,4-dihydroxy-a-methyl-, D- (8CI), (aR)-a-Hydrazinyl-3,4-dihydroxy-a-methylbenzenepropanoic acid, MK 485, (2R)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic Acid, ent-Carbidopa, Benzenepropanoicacid, a-hydrazino-3,4-dihydroxy-a-methyl-, (R)-, Benzenepropanoicacid, a-hydrazino-3,4-dihydroxy-a-methyl-, (aR)- (9CI), Hydrocinnamic acid, a-hydrazino-3,4-dihydroxy-a-methyl-, D- (8CI), Mk 485

Description

Stability Hygroscopic
Applications R-(+)-Carbidopa is an inhibitor of DOPA decarboxylase, which plays a significant role in the prevention of the conversion of L-DOPA (D533751) to dopamine (D533780). Studies has also indicated the inhibitory effects of towards L-DOPA in human liver prepns and as well as 5-hydroxytryptophan (H975700).
References Vogel, W.H. et al.: Arch. Int. Pharmacodyn. Ther. 198, 85 (1972);

• Brand: TRC

Chemical properties

• Molecular weight: 226.23
• Formula: C₁₀H₁₄N₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C10H14N2O4/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6/h2-4,12-14H,5,11H2,1H3,(H,15,16)/t10-/m1/s1
• InChI key: InChIKey=TZFNLOMSOLWIDK-SNVBAGLBSA-N
• SMILES: C[C@](Cc1ccc(O)c(O)c1)(NN)C(=O)O