N-Carbethoxy-4-piperidone

CAS: 29976-53-2

Ref. TR-C176120

Product Information

• Name: N-Carbethoxy-4-piperidone
• Synonyms: Ethyl 4-Oxopiperidine-1-carboxylate, Loratadine Imp. H (EP), Loratadine Impurity H, 1-(Carboethoxy)-4-piperidinone, 1-(Carboethoxy)-4-piperidone, 1-Carbethoxy-4-Piperidone, 1-Carbethoxypiperidin-4-one, 1-Ethoxycarbonyl-4-oxopiperidine, 1-Ethoxycarbonyl-4-piperidinone, 1-Ethoxycarbonyl-4-piperidone, 1-Piperidinecarboxylic Acid, 4-Oxo-, Ethyl Ester, 4-Oxo-1-piperidinecarboxylic acid ethyl ester, 4-Oxo-Piperidine-1-Carboxylic Acid Ethyl Ester, 4-Piperidone-1-Carboxylic Acid Ethyl Ester, 4-Piperidone-N-Carboxylic Acid Ethyl Ester, Aurora Ka-3057, Ethyl 4-Oxopiperidine-1-Carboxylate, Ethyl 4-Piperidone-1-Carboxylate, Ethyl 4-Piperidone-N-Carboxylate, Ethyl 4-oxo-1-piperidinecarboxylate, N-Carbethoxy-4-piperidinone, N-Carbithoxy-4-Piperidone, N-Carboethoxy-4-piperidone, N-Ethoxycarbonyl-4-Piperidone, N-Ethoxycarbonyl-4-piperidinone, NSC 139022

Description

Impurity Loratadine EP Impurity H
Applications N-Carbethoxy-4-piperidone (Loratadine EP Impurity H) is used in the preparation of 3-hydrazinopyridazines as antihypertensive agents as well as γ-carboline derivatives as potential serotonergic agents. N-Carbethoxy-4-piperidone is also an impurity of Loratadine (L469575).
References Schenker, E. et al.: Arsneim.-Forsch., 29, 1835 (1979); El-Kader, A. et al.: Mans. J. Pharm. Sci., 6, 1 (1989); Albu, M. et al.: J. Liq. Chrom. Rel. Technol., 32, 2569 (2009);

• Brand: TRC

Chemical properties

• Molecular weight: 171.19
• Formula: C₈H₁₃NO₃
• Color/Form: Neat
• InChI: InChI=1S/C8H13NO3/c1-2-12-8(11)9-5-3-7(10)4-6-9/h2-6H2,1H3
• InChI key: InChIKey=LUBGFMZTGFXIIN-UHFFFAOYSA-N
• SMILES: CCOC(=O)N1CCC(=O)CC1