Product Information
Name:Carbonochloridic Acid 1,2,2,2-Tetrachloroethyl Ester
Controlled Product
Synonyms:
- Chloroformic Acid 11,2,2,2-Tetrachloroethyl Ester
- 1,2,2,2-Tetrachloroethyl Carbonochloridate
- 1,2,2,2-Tetrachloroethyl Chloroformate
Brand:TRC
Description:
Applications Carbonochloridic Acid 1,2,2,2-Tetrachloroethyl Ester is used in the synthesis of Doxorubicin (D558000), is used as an antineoplastic. Also used in the synthesis of metabolites of Docetaxel (D494420), a semisynthetic derivative of Paclitaxel. An antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antine oplastic.
References Di Marco, A., et al.: Cancer Chemother. Rep., (part 1), 53, 33 (1969), Mihich, E. and Ehrke, M.J.: Transplant. Proc., 16, 499 (1984); Ringel, I., et al.: J. Natl. Cancer Inst., 83, 288 (1991), Extra, J.-M., et al.: Cancer Res., 53, 1037 (1993)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:246.304
Formula:C3HCl5O2
Color/Form:Neat
InChI:InChI=1S/C3HCl5O2/c4-1(3(6,7)8)10-2(5)9/h1H
InChI key:InChIKey=RINXZIYBNVEZRT-UHFFFAOYSA-N
SMILES:O=C(Cl)OC(Cl)C(Cl)(Cl)Cl
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