Product Information
Name:Carbovir Monophosphate
Controlled Product
Synonyms:
- rel-2-Amino-1,9-dihydro-9-[(1R,4S)-4-[(phosphonooxy)methyl]-2-cyclopenten-1-yl]-6H-purin-6-one
- cis-(±)-2-Amino-1,9-dihydro-9-[4-[(phosphonooxy)methyl]-2-cyclopenten-1-yl]-6H-purin-6-one
- Carbovir 5’-Phosphate
- Abacavir - In House Impurity
- Abacavir Impurities
Brand:TRC
Description:Impurity Abacavir - In House ImpurityApplications Carbovir Monophosphate (Abacavir - In House Impurity) is a phosphorylated metabolite of the human immunodeficiency virus inhibitor Carbovir (C177740). It is converted from Abacavir 5’-phosphate by the enzyme N6-Methyl-AMP aminohydrolase (1,2,3).References (1) Murakami, E., et al.: J Med Chem. 25, 5902 (2011) (2) Vince, R.: Nucl. Acids Symp. Ser., 25, 193 (1991) (3) Schinkmanova, M. et al.: Biochem. Pharmacol., 71, 1370 (2006)
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Chemical properties
Molecular weight:327.23
Formula:C11H14N5O5P
Color/Form:Neat
InChI:InChI=1S/C11H14N5O5P/c12-11-14-9-8(10(17)15-11)13-5-16(9)7-2-1-6(3-7)4-21-22(18,19)20/h1-2,5-7H,3-4H2,(H2,18,19,20)(H3,12,14,15,17)
InChI key:InChIKey=OJDRNVIJFVCXOM-UHFFFAOYSA-N
SMILES:Nc1nc(=O)c2ncn(C3C=CC(COP(=O)(O)O)C3)c2[nH]1
Technical inquiry about: Carbovir Monophosphate
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